Molecular pathology of schizophrenia: more than one disease process?

in Florence showed some symptomatic improvement with only minor side effects, but this requires confirmation in a controlled trial. Cyclosporin A does not cause bone marrow depression; but reports of the development of lymphoma in patients treated with the drug after transplantation,6 and indeed in patients treated with other immunosuppressive drugs,7 mean that immunosuppression should be used circumspectly. Another approach is based on the finding that suppressor lymphocyte activity is depressed during acute relapses in multiple sclerosis.8 This has raised the possibility of enhancing suppressor cell activity therapeutically, and is yet another potentially promising line of investigation.